Publications 2000 – 2004

46. Rosen CJ, Ackert-Bicknell CL, Adamo ML, Shultz KL, Rubin J, Donahue LR, Horton LG, Delahunty KM, Beamer WG, Sipos J, Clemmons D, Nelson T, Bouxsein ML, Horowitz M. Congenic mice with low serum IGF-1 have increased body fat, reduce bone mineral density, and an altered osteoblast differentiation program. Bone, 2004; 35 (5): 1046-58.
45. Riggs BL, Melton LJ, Robb RA, Camp JJ, Atkinson EJ, Peterson JM, Rouleau PA, McCollough CH, Bouxsein ML, Khosla S. Population-based study of age and sex differences in bone volumetric density, size, geometry and structure at different skeletal sites. J Bone Min Res 2004; 19:1945-54.
44. Holmen SL, Giambernardi TA, Zylstra CR, Buckner-Berghaus BD, Resau JH, Hess JF, Glatt V, Bouxsein ML, Ai M, Warman ML, Williams BO. Decreased bone density and limb deformities in mice carrying mutations in both Lrp5 and Lrp6. J Bone Min Res 2004; 19: 2033-40.
43. Bouxsein ML, Kaufman J, Tosi L, Cummings S, Lane J, Johnell O. Recommendations for care of the osteoporotic fracture patient to reduce the risk of future fracture. J Am Acad Orthop Surg 2004; 12 (6): 385-95.
42. Seeherman H, Bouxsein M, Kim H, Li R, Li XJ, Aiolova M, Wozney JM. Recombinant human bone morphogenetic protein-2 delivered in an injectable calcium phosphate paste accelerates osteotomy healing in a nonhuman primate model. J Bone Jt Surg 2004 ; 86-A: 1961-72.
41. Bertone AL, Pittman DD, Bouxsein ML, Li J, Clancy B, Seeherman HJ. Adenoviral-mediated transfer of human BMP-6 gene accelerates healing in a rabbit ulnar osteotomy model. J Orthop Res 2004; 22: 1261-70.
40. Johnston JD, Small CF, Bouxsein ML, Pichora DR. Mechanical properties of the scapholunate ligament correlate with bone mineral density measurements of the hand. J Orthop Res 2004; 22 (4): 867-871.
39. Bouxsein ML, Uchiyama T, Rosen CJ, Shultz KL, Donahue LR, Turner CH, Sen S, Churchill G, Müller RA, Beamer, WG. Mapping quantitative trait loci for vertebral trabecular bone volume fraction and microarchitecture in mice. J Bone Min Res 2004; 19: 587-599.
38. Kacena M, Shivdasani RA, Wilson K, Yougen X, Troiano N, Nazarian A, Gundberg C, Bouxsein ML, Lorenzo JA, Horowitz MC. Unsuspected megakaryocyte-osteoblast interaction revealed through increased bone formation in mice deficient in transcription factors GATA-1 and NF-E2. J Bone Min Res 2004; 19:652-660.
37. Yakar S, Setser J, Zhao H, Atannard B, Haluzik M, Glatt V, Bouxsein M, Kopchick J, LeRoith D. Inhibition of growth hormone action improves insulin sensitivity in liver IGF-1 deficient mice. J Clin Invest 2004; 113: 96-105.
36. Tingart MJ, Bouxsein ML, Zurakowski DE, Warner JJP, Apreleva M. Three-dimensional distribution of bone density in the proximal humerus. Calcif Tissue Int 2003; 73 (6): 531-6.
35. Li RH, Bouxsein ML, Blake CA, D’August D, Li XJ, Wozney JM, Kim H, Seeherman, HJ. rhBMP-2 injected in a calcium phosphate paste (a-BSM) accelerates healing in the rabbit ulnar osteotomy model. J Orthop Res 2003; 21 (6): 997-1004.
34. Turner CH, Sun Q, Schriefer J, Pitner N, Price R, Bouxsein ML, Rosen CJ, Donahue LR, Shultz KL, Beamer WG. Congenic mice reveal gender-specific genetic regulation of femoral structure and strength. Calcif Tissue Int 2003; 73 (3): 297-303.
33. Black DM, Greenspan SL, Ensrud KE, Palermo L, McGowan JA, Lang TF, Garnero P, Bouxsein ML, Bilezikian JP, Rosen CJ. The effects of PTH and alendronate alone or in combination in post-menopausal osteoporosis. N Engl J Med 2003; 349 (13): 1207-1215.
32. Einhorn TA, Majeska RJ, Mohaideen A, Kagel EM, Bouxsein ML, Turek TJ, Wozney JM. A single percutaneous injection of recombinant human bone morphogenetic protein-2 accelerates fracture repair. J Bone Jt Surg 2003; 85-A: 1425-35.
31. Bonner FJ, Sinaki M, Grabois M, Shipp KM, Lane JM, Lindsay R, Gold DT, Cosman F, Bouxsein ML, Weinstein JN, Gallagher RM, Melton LJ, Salcido RS, Gordon SL. Health professional’s guide to rehabilitation of the patient with osteoporosis. Osteoporosis Int 2003; 14 (suppl 2): S1-S22.
30. Babij P, Zhao W, Small C, Reddy PS, Yaworsky PJ, Bouxsein M, Bodine PVN, Robinson JA, Moran RA, Kharode Y, Bex F. High bone mass in transgenic mice expressing a mutant human low-density lipoprotein receptor related protein 5 (LRP5). J Bone Min Res 2003; 18: 960-974.
29. Muller ME, Webber CE, Bouxsein ML. Predicting the failure load of the distal radius. Osteoporosis Int 2003; 14: 345-52.
28. Zhang M, Xuan S, Bouxsein ML, von Stechow D, Faugere MC, Malluche H, Zhao G, Rosen CJ, Efstratiadis A, Clemens TL. Osteoblast-specific knockout of the insulin-like growth factor (IGF) receptor gene reveals an essential role of IGF-1 signaling in bone matrix mineralization. J Biol Chem 2002; 277 (46): 44005-12.
27. Shultz K, Donahue LR, Bouxsein ML, Baylink D, Rosen CJ, Beamer WG. Genetic decomposition of quantitative trait loci for high and low volumetric bone mineral density using congenic strains of mice. J Bone Min Res 2003; 18 (2) 175-85.
26. Li G, Bouxsein ML, Luppen C, Li XJ, Wood M, Seeherman HJ, Wozney JM, Simpson H. Bone consolidation in enhanced by rhBMP-2 in a rabbit model of distraction osteogenesis. J Orthop Res 2002; 20: 779-788.
25. Nicholson PHF and Bouxsein ML. Bone marrow influences quantitative ultrasound measurements in human cancellous bone. Ultrasound in Medicine and Biology 2002; 28: 369-75.
24. Nicholson PHF, Bouxsein ML. Effect of temperature on ultrasonic properties of the calcaneus in situ. Osteoporosis Int 2002; 13 (11): 888-892.
23. Bouxsein ML, Palermo L, Yeung C, Black DM. Digital x-ray radiogrammetry predicts hip, wrist and vertebral fracture risk in elderly women: A prospective analysis from the Study of Osteoporotic Fractures. Osteoporosis Int 2002; 13: 358-365.
22. Bouxsein ML, Rosen CJ, Ackert CA, Shultz KL, Donahue LR, Adamo M, Powell DR. Turner CH, Müller RA, Beamer WG. Testing the relationship of IGF-1 to bone mineral density, skeletal morphology and fragility in vivo: Generation of a new congenic mouse strain. J Bone Min Res 2002; 17: 570-579.
21. Luppen CA, Blake CA, Ammirati KM, Stevens ML, Li XJ, Seeherman HJ, Wozney JM, Bouxsein ML. rhBMP-2 enhances osteotomy healing in glucocorticoid treated rabbits. J Bone Min Res 2002; 17: 301-310.
20. Bouxsein ML, Turek TJ, Blake CA, Stevens ML, Li XJ, Seeherman HJ, Wozney JM. Recombinant human bone morphogenetic protein-2 accelerates osteotomy healing in rabbit model. J Bone Jt Surgery 2001; 83-A: 1219-1230.
19. Turner CHT, Hsieh Y-F, Müller R, Bouxsein ML, Rosen CJ, McCrann ME, Donahue LR, Beamer WG. Variation in bone biomechanical properties, microstructure and density in BxH recombinant inbred mice. J Bone Min Res. 2001; 16: 206-213.
18. Nicholson PHF, Bouxsein ML. Quantitative ultrasound does not reflect mechanically induced damage in cancellous bone. J Bone Min Res 2000; 15:2467-2472.
17. McClean RR, Hannan MT, Epstein BE, Bouxsein ML, Cupples LA, Murabito J, Kiel DP. Elderly cohort study subjects unable to return for follow-up have lower bone mass than those who can return. Am J Epidemiology 2000; 151: 689-692.
16. Nicholson PHF, Strelitzki R, Cleveland RO, Bouxsein ML. Scattering of ultrasound in cancellous bone: fundamental concepts and predictions from a theoretical model. J Biomechanics 2000; 33 (4): 503-506.
15. Turner CHT, Hsieh Y-F, Müller R, Bouxsein ML, Baylink DJ, Rosen CJ, Grynpas MD, Donahue LR, Beamer WG. Genetic regulation of cortical and trabecular bone strength and microstructure in inbred strains of mice. J Bone Min Res 2000; 15: 1126-1131.
14. Bouxsein ML, Parker RA, Greenspan SL. Forearm bone mineral density cannot be used to predict the response to alendronate therapy. Osteoporosis Int 2000; 10: 505-509.