The Bouxsein group employs a multidisciplinary strategy with state-of-the-art technologies to study the causes, detection and treatment of skeletal fragility. One in two women and one in five men over the age of 50 will suffer a fragility fracture in their remaining lifetime. Thus, our ultimate goal is to reduce the burden of fractures due to osteoporosis and other bone disorders.

We have several ongoing projects:

  1. The evaluation of novel technologies for non-invasive or minimally-invasive assessment of bone fragility and fracture risk in osteoporosis and other diseases associated with skeletal fragility;
  2. Identification of the biomechanical factors that contribute to vertebral fractures;
  3. Identification of the key factors that influence musculoskeletal deterioration following reduced mechanical loading;
  4. Evaluating the biomechanical effects of new therapies for osteoporosis and fracture healing;
  5. Vertebral loading analysis in astronauts after long duration spaceflight on the ISS.

The Bouxsein group includes biomechanical engineers and biologists, and we collaborate closely with molecular biologists, clinicians, imaging specialists, and musculoskeletal epidemiologists. We are funded by grants from the National Institute of Arthritis, Musculoskeletal and Skin Diseases, the National Institute on Aging, National Institute of Child Health and Development, and NASA.

Thanks to our Excellent 2019 Research Students!

Thank you to our 2019 lab interns! Pictured left to right: Isabelle…

Drinking red wine on Mars may protect against muscle atrophy

A new study by researchers at BIDMC, including Dr. Mary Bouxsein,…

New Publications: Congratulations to Authors!

Congratulations on the publications of two new manuscripts! 'In…

Congratulations to Dr. Bouxsein for being awarded two NASA health and human performance proposals!

NASA's Human Research Program and Space Biology Program announced…

Congratulations to Fjola Johannesdottir on her Promotion to Instructor!

Congratulations to Dr. Fjola Johannesdottir for her promotion…

Thank You to our 2018 Summer Interns!

Thank you to our 2018 summer lab interns: Frank Ma (Tufts…